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Search Results for " ccr1 antagonist "

20

Compounds

Cat No. Product Name Synonyms Targets
T10708 CCR1 antagonist 6 CCR
CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).
T30258 AZD-4818 CCR1 antagonist CCR
AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.
T10710 CCR1 antagonist 9 CCR
CCR1 antagonist 9 is an effective and selective CCR1 antagonist (IC50: 6.8 nM in calcium flux assay).
T14899 CCR1 antagonist 8 CCR
CCR1 antagonist 8, a third azaindazole series compound, is a CCR1 antagonist (IC50: 1.8 nM in Ca2+ flux assay).
T10709 CCR1 antagonist 7 CCR
CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].
T15253 CCX354 CCR1 antagonist 1,CCX-354,CCX 354 CCR
CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.
T64242 CCR1 antagonist 11 hydrochloride
CCR1 antagonist 11 hydrochloride (A1B1) is an orally active CCR1 antagonist that acts on hCCR1 (IC50: 0/.03 μM), mCCR1 (IC50: 0.58 μM), rCCR1 (IC50: 0.32 μM). 11 hydrochloride can be used to study rheumatoid arthritis an...
T28072 MLN-3897 AVE9897,AVE 9897,CCR1 antagonist 10,AVE-9897 CCR
MLN-3897 (CCR1 antagonist 10) is an orally active antagonist of CCR1 with a Ki of 2.3 nM for 125I-MIP-1α binding to THP-1 cell membranes. MLN-3897 inhibits Akt signaling and MM cell survival and proliferation.
T2375 BX471 BX 471,BX-471,ZK-811752 CCR
BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.
T28072L MLN-3897 TFA MLN-3897 TFA(1010731-97-1 Free base) CCR
MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.
TQ0283 RS102895 CCR
RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.
T11699 J-113863 CCR
J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptor...
T5384 RS 504393 CCR
RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).
T26861 BMS-817399 BMS817399 CCR
BMS-817399 is an orally active antagonist of CCR1 with IC50s of binding affinity and chemotaxis inhibition potencies and can be used in studies about rheumatoid arthritis.
T23492 UCB 35625 Others
chemokine CCR1 and CCR3 receptor antagonist
T14845 BX471 hydrochloride ZK-811752 hydrochloride Others
BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4.
T31061 CP-481715 CP 481,715,CP-481,715,CP481715,CP481,715
CP 481715 is an effective selective CCR1 antagonist with potential therapeutic significance for inflammatory diseases.
T26849 BMS-457
BMS-457 is a potent, CCR1-selective antagonist.
T71905 BX-513 HCl
BX-513 HCl is a selective CCR1 receptor antagonist.
T68427 MLN-3897 citrate
MLN-3897 citrate is a C-C Motif Chemokine Receptor 1 (CCR1) antagonist potentially for the treatment of multiple sclerosis and rheumatoid arthritis.
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